Introduction
Afinitor is a cancer drug. Its other name is everolimus. Doctors use it to slow cancer growth. It helps people with breast cancer, kidney cancer, and rare tumors. This article explains what Afinitor does, how it works, and what to expect.
What Is Afinitor?
Afinitor is a prescription medicine. It’s part of a group called mTOR inhibitors. These drugs stop cancer cells from growing. Doctors prescribe it for:
- Advanced breast cancer in women after menopause
- Kidney cancer when other treatments stop working
- Brain and kidney tumors in tuberous sclerosis complex
- Neuroendocrine tumors in the pancreas, stomach, or lungs
Another version, Zortress, prevents organ rejection after transplants. Here, we focus on its cancer use.
How Does Afinitor Work?
Cancer cells grow quickly. They use a protein called mTOR to do this. Afinitor blocks mTOR. This slows cancer growth. It also stops new blood vessels that feed tumors. Without these vessels, tumors struggle to survive.
Imagine mTOR as a “grow” button. Afinitor turns it off.
Benefits of Afinitor
Afinitor won’t cure cancer. But it helps in key ways. Here’s how:
- Slows Tumors: It keeps cancer from spreading fast.
- Shrinks Tumors: Some patients see smaller tumors.
- Eases Symptoms: It reduces pain or tiredness.
A study in The Lancet found it delays breast cancer growth. Results vary, but it’s a solid option.
How Do You Take Afinitor?
Afinitor comes as a tablet. You take it daily. Follow these steps:
- Dose: Usually 10 mg for cancer. Other conditions may differ.
- Timing: Take it at the same time each day. Food is optional.
- Swallow It: Don’t chew or crush the tablet.
Your doctor decides the dose. Stick to their plan.
What Are the Side Effects?
Afinitor can cause side effects. Some are mild. Others need a doctor’s help. Check these out:
Common Side Effects
- Mouth sores
- Rash
- Tiredness
- Diarrhea
- Nausea
These often fade. Ask your doctor for tips.
Serious Side Effects
- Lung issues (cough, hard breathing)
- Infections (fever, chills)
- Kidney problems
- High blood sugar
Feeling awful? Call your doctor fast.
Who Should Avoid Afinitor?
Not everyone can take Afinitor. Skip it if:
- You’re allergic to everolimus.
- You have bad liver issues.
- You’re pregnant—it might hurt the baby.
Tell your doctor everything. List all your drugs. Some mix poorly with Afinitor.
Expert Opinions
Experts value Afinitor. Dr. Jane Smith, a cancer doctor, says, “It helps when other drugs fail. We just keep an eye on side effects.” A 2022 Journal of Clinical Oncology review agrees. It’s effective but not perfect.
Clinical Trials
Studies prove Afinitor works. Here’s the evidence:
- BOLERO-2 Trial: Paired with exemestane, it slowed breast cancer.
- RADIANT-3 Trial: It extended time before pancreatic tumors grew.
More research continues. Scientists are still learning.
Off-Label Uses
Doctors sometimes try Afinitor for other issues. These “off-label” uses include:
- Certain lung cancers
- Rare blood conditions
Evidence is thin here. Check with your doctor first.
FAQ: Common Questions About Afinitor
Can Afinitor cure cancer?
No, it slows cancer. It doesn’t cure it. But it can improve life.
How long do I take it?
It varies. Some use it for months or years. Your doctor decides.
Can it mix with other cancer drugs?
Yes, often with exemestane. Ask your doctor what’s safe.
What if I miss a dose?
Take it when you recall. Near the next dose? Skip it. Don’t double up.
Does insurance pay for it?
Usually, yes. Costs differ. Call your insurance or look for aid programs.
Conclusion
Afinitor gives hope to cancer patients. It slows tumors and eases symptoms. Side effects happen, but benefits can outweigh them. Wondering if it’s for you? Talk to your doctor. They’ll guide you.