Tadalafil is an ED drug better known as generic Cialis.

What is Tadalafil?

You know Cialis? Same drug. Just not branded.

Also known as “ED,” erectile dysfunction is when you can’t get an erection hard enough for sex. The perp is an enzyme called PDE5. It makes arteries at the base of the penis to too tight to let blood through. When blood can’t mix it up with the muscle tissues in the penis, this makes getting an erection pretty difficult.

Tadalafil what you call a PDE5 inhibitor. These medicines work in the body by (you guessed it) limiting the action of PDE5. This allows blood vessels to dilate and relax, increasing blood flow to the penis.

The result is a harder and more reliable erection.

What Tadalafil dosage is right for me?

There are two forms of Tadalafil available. The daily form is taken every day, and is essentially ‘effective’ all of the time. The weekend form is taken on demand, and the effects can last for up to 36 hours.

Choosing Tadalafil daily 2.5mg and 5mg

This option suits men who are happy to take one tablet at the same time each day. It allows for more spontaneity as the low dose offers continuous treatment, therefore sex can be enjoyed without having to plan when to take medication.  If the 2.5mg tablet does not provide sufficient results, then your doctor has the option to increase to 5mg. 

Choosing Tadalafil ‘weekend’ 10mg and 20mg

The term ‘weekend pill’ refers to the fact that these doses can be effective for up to 36 hours. The term ‘effective’ does not mean a constant erection. This means that the drug will help to produce an erection when sexually stimulated during the ‘effective’ time period. If you develop an erection which does not go away or lasts for more than four hours continuously, seek medical attention right away. 

The 10mg is usually the starting dose and is taken around 30 minutes prior to having sex. The Tadalafil 20mg dose is also taken 30 minutes before sex and can be prescribed when the lower dose has not produced completely satisfactory results. 

Tadalafil vs Cialis: What’s the difference?

Tadalafil is the generic edition of the branded version of this drug which has been available since 2003, and is one of the leading medications in the world for ED. In 2017, the patent on the drug expired, making generic Cialis legally available.

How effective are erectile dysfunction treatments?

This will likely depend on your needs, circumstances and genetics. Each medication comes with some advantages. Cialis and other PDE5 inhibitors, for example, are tablets and more convenient to take, while Caverject is thought to have fewer interactions with other medications.

Whichever treatment is suitable for you, there are many options available and your prescribing clinician should be able to offer a treatment that is both safe and effective. Studies have shown that PDE5 inhibitors are helpful for the vast majority of those using them. For those who find these treatments are ineffective, or unsuitable, PGE1 prostaglandins may be able to provide the desired results.

How to take Tadalafil

It’s important to understand that, while Tadalafil can be taken either as an as-needed drug or as a daily medication, you shouldn’t take as-needed prescriptions as a daily regimen. There’s a simple reason for that: dose size.

According to the FDA, daily doses of tadalafil are typically prescribed much smaller than as-needed. As-needed medication will typically be prescribed either as a 10mg or 20mg dosage, whereas a daily dose will be a fraction of that—typically between 2.5mg and 5mg. 

You almost certainly don’t need 20mg daily tadalafil prescription. Daily doses of smaller measures will maintain the drug in your system without multiplying your risk of side effects, but taking 20mg a day would offer no additional benefits—just added risks.

Tadalafil is a proven safe and effective option for treating erectile dysfunction, and it certainly could be the right solution for you. But there are other factors to consider, even beyond the potential side effects and drug interactions. 

One question you should ask yourself is whether your ED might be psychological—whether insecurity, fear of intimacy, or low self esteem might be contributing to the problem. 

Conditions like anxiety and depression can play a role in performance issues, and if you think that might be the case for you, consult a psychiatrist or mental health professional to see if other treatments might be helpful.

Tadalafil might still be a solution, even if part of the problem is in your other head. If you’re ready to look at treatment options, consult your healthcare provider to see if Tadalafil can help.

What are the Advantages of Taking Tadalafil?

Every ED medication has their own set of advantages. Here are a few things that make tadalafil unique:

  • It’s long-lasting. In fact, it’s the longest lasting ED medication on the market. One dosage can help erections for up to 36 hours. What’s nice about this is that it means you don’t have to take it right before sex. 
  • You can take it daily. Tadalafil can be taken as-needed or daily at a lower dosage of 2.5 or 5mg a day. If you take it daily, spontaneous sex is much easier and, because you’re taking it at a lower dose, you may notice fewer side effects. To read more about the benefits of using tadalafil daily, check out our guide to daily-use Cialis.

Tadalafil side effects

Common side effects, affecting one to ten in every 100 patients, include: headaches, back aches, muscle pain, discomfort in arms and legs, flushing, nasal congestion and digestive issues.

If you experience any side effects with this medication, you can report them to the MHRA’s (Medicines and Healthcare Products Regulatory Agency) yellow card scheme, which tracks all known side effects relating to medications in the UK in order to provide the most accurate data possible.

Comparing Tadalafil to Viagra

Cialis and Viagra are two of the most popular erectile dysfunction medications on the market.

Both Cialis and Viagra are PDE5 inhibitors, but the key difference that separates tadalafil from Viagra is that Viagra is a shorter term medication, typically resulting in four to six hours of effects, while Cialis can work from a day to a day and a half. 

This means that, in general, Viagra has been prescribed as a sort of in-the-moment solution; date night is going well, you’re heading back to her place, so you take a pill to coincide with your best laid (pun intended) plans. 

Tadalafil, on the other hand, is more of a carpet bomb medication with regards to your down-and-dirty schedule. Its wider window of efficacy means that a morning dose has the capacity to prepare you for some afternoon delight and/or late night activities.

And that’s why tadalafil is also an exceptionally better option when your sex life isn’t so neatly designed as to fit into your iCal at regular intervals; if your partner can be game whenever, tadalafil as a daily medication is designed to help you meet the challenge.

Dealing with ED long term

ED, while not necessarily a sign of a deeper physical health condition, has a major effect on those that suffer from it. For most, the psychological issues that cause the problems become self-perpetuating, resulting in further anxieties and the worsening of the condition. Talking therapies are very effective at breaking this cycle, particularly CBT (cognitive behavioural therapy), where, with practice, you can recognise how negative thoughts build on other negative thoughts and avoid this from escalating. Physical causes can often be treated with medications or surgery. For example, high blood pressure is effectively lowered with statins. In the meantime, ED treatments, such as Viagra and Cialis, manage erectile dysfunction symptoms, but it also is important to understand that there are many options available to manage it and its underlying causes.

How to Buy Tadalafil at the Lowest Price

If you’re looking to spend the least amount possible for tadalafil, these tips should help.

  • Go with a generic. As shown above, generics have the same effective ingredients while costing much less. In fact, the U.S. Food and Drug Administration requires that generic drugs have the same key ingredients, strength, dosage and administration as the brand name versions.
  • Try to use your insurance plan. Depending on your provider and plan, ED medication may be covered. Check your insurance’s formulary, which is a complete list of drugs they cover. It should be on their website. Can’t find it? You can also call the number on the back of your insurance card and ask a representative. 
  • Consider another ED medication. There are other medications that may help and that come at a lower price. Sildenafil is a great example. It’s the active ingredient in Viagra® and, though it lasts for a shorter time than tadalafil, it can be just as effective.

One thing you should never do is try to cut corners. ED medications are frequently faked and there are many counterfeits out there. 

These fake meds are usually sold online and don’t require a prescription — something that should be a red flag. Another thing to be wary of is if the price seems drastically low. 

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Last Update: 30 March 2024